Επιλεγμένες Δημοσιεύσεις


1. Chalkias A, Xenos M. Relationship of Effective Circulating Volume with Sublingual Red Blood Cell Velocity and Microvessel Pressure Difference: A Clinical Investigation and Computational Fluid Dynamics Modeling. J Clin Med 2022;11(16):4885.
2. Chalkias A, Laou E, Mermiri M, Michou A, Ntalarizou N, Koutsona S, Chasiotis G, Garoufalis G, Agorogiannis V, Kyriakaki A, Papagiannakis N. Microcirculation-guided treatment improves tissue perfusion and hemodynamic coherence in surgical patients with septic shock. Eur J Trauma Emerg Surg 2022. doi: 10.1007/s00068-022-01991-2. In press.
3. Chalkias A, Laou E, Papagiannakis N, Varvarousi G, Ragias D, Koutsovasilis A, Makris D, Varvarousis D, Iacovidou N, Pantazopoulos I, Xanthos T. Determinants of venous return in steady-state physiology and asphyxia-induced circulatory shock and arrest: an experimental study. Intensive Care Med Exp 2022;10:13.
4. Chalkias A, Laou E, Papagiannakis N, Spyropoulos V, Kouskouni E, Theodoraki K, Xanthos T. Assessment of Dynamic Changes in Stressed Volume and Venous Return during Hyperdynamic Septic Shock. J Pers Med 2022;12:724.
5. Chalkias A, Papagiannakis N, Saugel B, Flick M, Kolonia K, Angelopoulou Z, Ragias D, Papaspyrou D, Bouzia A, Ntalarizou N, Stamoulis K, Kyriakaki A, Eugen-Olsen J, Laou E, Arnaoutoglou E. Association of Preoperative Basal Inflammatory State, Measured by Plasma suPAR Levels, with Intraoperative Sublingual Microvascular Perfusion in Patients Undergoing Major Non-Cardiac Surgery. J Clin Med 2022;11:3326.
6. Laou E, Papagiannakis N, Tsiaka A, Tsapournioti S, Chatzikallinikidis K, Mantzaflaras G, Karadontas I, Eugen-Olsen J, Chalkias A. Soluble urokinase receptor levels are not affected by the systemic inflammatory response to anesthesia and operative trauma. Eur Surg Res 2022. doi: 10.1159/000524433. In press.
7. Chalkias A. Current Challenges in the Management of Sepsis and Septic Shock: Personalized, Physiology-Guided Treatment. J Clin Med 2022;11(15):4565.
8. Russotto V, Myatra SN, Laffey JG, Tassistro E, Antolini L, Bauer P, Lascarrou JB, Szuldrzynski K, Camporota L, Pelosi P, Sorbello M, Higgs A, Greif R, Putensen C, Agvald-Öhman C, Chalkias A, Bokums K, Brewster D, Rossi E, Fumagalli R, Pesenti A, Foti G, Bellani G; INTUBE Study Investigators. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries. JAMA 2021;325:1164-72.
9. Chalkias A, Mongardon N, Boboshko V, Cerny V, Constant AL, De Roux Q, Finco G, Fumagalli F, Gkamprela E, Legriel S, Lomivorotov V, Magliocca A, Makaronis P, Mamais I, Mani I, Mavridis T, Mura P, Ristagno G, Sardo S, Papagiannakis N, Xanthos T; PERIOPCA Consortium. Clinical practice recommendations on the management of perioperative cardiac arrest: A report from the PERIOPCA Consortium. Crit Care 2021;25:265.
10. Chalkias A, Papagiannakis N, Mavrovounis G, Kolonia K, Mermiri M, Pantazopoulos I, Laou E, Arnaoutoglou E. Sublingual microcirculatory alterations during the immediate and early postoperative period: A systematic review and meta-analysis. Clin Hemorheol Microcirc 2022;80:253-65.
11. Chalkias A, Spyropoulos V, Georgiou G, Laou E, Koutsovasilis A, Pantazopoulos I, Kolonia K, Vrakas S, Papalois A, Demeridou S, Gourgoulianis K, Dontas I, Kaparos G, Baka S, Xanthos T. Baseline Values and Kinetics of IL-6, Procalcitonin, and TNF-α in Landrace-Large White Swine Anesthetized with Propofol-Based Total Intravenous Anesthesia. Biomed Res Int 2021;2021:6672573.
12. Chalkias A, Pantazopoulos I, Papagiannakis N, Skoulakis A, Laou E, Kolonia K, Ntalarizou N, Tourlakopoulos K, Pagonis A, Kampolis C, De Guadiana Romualdo LG, Ragias D, Eugen-Olsen J, Gourgoulianis K, Arnaoutoglou E; SPARCOL Investigators. Sinus bradycardia is associated with poor outcome in critically ill patients with COVID-19 due to the B.1.1.7 Lineage. Toxicol Rep 2021;8:1394-8.
13. Chalkias A, Koutsovasilis A, Laou E, Papalois A, Xanthos T. Measurement of mean systemic filling pressure after severe hemorrhagic shock in swine anesthetized with propofol-based total intravenous anesthesia: implications for vasopressor-free resuscitation. Acute Crit Care 2020;35:93-101.
14. Chalkias A, Arnaoutoglou E, Xanthos T. Personalized physiology-guided resuscitation in highly monitored patients with cardiac arrest-the PERSEUS resuscitation protocol. Heart Fail Rev 2019;24:473-80.
15. Kyriazopoulou E, Karakike E, Ekmektzoglou K, Kyprianou M, Gkolfakis P, Chalkias A, Kouskouni E, Xanthos T. Sinus Bradycardia During Targeted Temperature Management: A Systematic Review and Meta-Analysis. Ther Hypothermia Temp Manag 2020;10:17-26.
16. Chalkias A, Xanthos T. Airway Pressure Monitoring May Improve Small Airway Flow, Hemodynamics, and Tissue Oxygenation. Am J Respir Crit Care Med 2019;199:928-9.
17. Kontouli Z, Staikou C, Iacovidou N, Mamais I, Kouskouni E, Papalois A, Papapanagiotou P, Gulati A, Chalkias A, Xanthos T. Resuscitation with centhaquin and 6% hydroxyethyl starch 130/0.4 improves survival in a swine model of hemorrhagic shock: a randomized experimental study. Eur J Trauma Emerg Surg 2019;45:1077-85.
18. Chalkias A, Xanthos T, Papageorgiou E, Anania A, Beloukas A, Pavlopoulos F. Intraoperative initiation of a modified ARDSNet protocol increases survival of septic patients with severe acute respiratory distress syndrome. Heart Lung 2018;47:616-21.
19. Chalkias A, Pavlopoulos F, Papageorgiou E, Tountas C, Anania A, Panteli M, Beloukas A, Xanthos T. Development and Testing of a Novel Anaesthesia Induction/Ventilation Protocol for Patients With Cardiogenic Shock Complicating Acute Myocardial Infarction. Can J Cardiol 2018;34:1048-58.
20. Chalkias A, Athanasopoulos D, Xanthos T. Optimizing tissue perfusion during targeted temperature management. Injury 2016;47:2383-4.
21. Papapanagiotou P, Xanthos T, Gulati A, Chalkias A, Papalois A, Kontouli Z, Alegakis A, Iacovidou N. Centhaquin improves survival in a swine model of hemorrhagic shock. J Surg Res 2016;200:227-35.
22. Chalkias A, Spyropoulos V, Koutsovasilis A, Papalois A, Kouskouni E, Xanthos T. Cardiopulmonary Arrest and Resuscitation in Severe Sepsis and Septic Shock: A Research Model. Shock 2015;43:285-91.
23. Chalkias A, Xanthos T. Pathophysiology and pathogenesis of post-resuscitation myocardial stunning. Heart Fail Rev 2012;17:117-28.
24. Kakavas S, Chalkias A, Xanthos T. Vasoactive support in the optimization of post-cardiac arrest hemodynamic status: from pharmacology to clinical practice. Eur J Pharmacol 2011;667:32-40.

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